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At 24 hrs the plasma levels of sildenafil were being even now close to two hundred ng/mL, in comparison to approximately 5 ng/mL when sildenafil was dosed by itself. This really is in step with ritonavir's marked effects with a wide choice of P450 substrates. VIAGRA had no effect on ritonavir pharmacokinetics [see DOSAGE AND ADMINISTRATION and DRUG
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